Characterization of Overlap in Observational Studies


Overlap between treatment groups is required for non-parametric estimation of causal effects. If a subgroup of subjects always receives the same intervention, we cannot estimate the effect of intervention changes on that subgroup without further assumptions. When overlap does not hold globally, characterizing local regions of overlap can inform the relevance of causal conclusions for new subjects, and can help guide additional data collection. To have impact, these descriptions must be interpretable for downstream users who are not machine learning experts, such as policy makers. We formalize overlap estimation as a problem of finding minimum volume sets subject to coverage constraints and reduce this problem to binary classification with Boolean rule classifiers. We then generalize this method to estimate overlap in off-policy policy evaluation. In several real-world applications, we demonstrate that these rules have comparable accuracy to black-box estimators and provide intuitive and informative explanations that can inform policy making.

Proceedings of the Twenty-Third International Conference on Artificial Intelligence and Statistics (AISTATS)
Michael Oberst
Michael Oberst
PhD Student

Postdoc CMU, Incoming Asst Prof Johns Hopkins

David Sontag
David Sontag
Professor of EECS

My research focuses on advancing machine learning and artificial intelligence, and using these to transform health care.